The noise of the marine sewage vacuum pipeline system seriously impact the working and living environment of the crew, resulting in a strong demand for the noise reduction of the pipeline system by the crew. The characteristics of the noise source of the marine sewage vacuum pipeline system are analyzed to study the noise control technology of the pipeline system. It also proposes the noise reduction measures of the pipeline system, and carries out the design and performance test of the pipeline silencer. It plays an active role in improving the working and living environments of the engine room and living accommodation.